Person | Adolphe Merkle Institute | Université de Fribourg

PELLIZZONI Michela

Alumni

Postdoctoral researcher, BioNanomaterials

Adolphe Merkle Institute Chemin des Verdiers 4 CH-1700 Fribourg Switzerland

Office:	C011
Phone:	+41 26 300 9543
Email:	michela.pellizzoni@unifr.ch
	0000-0003-4294-0247

Projects team

Enzyme-catalyzed ATRP

Proteins such as hemoglobin, peroxidase or laccase are ATRPases, i.e. they catalyze ATRP

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Publications

Peroxidase Activity of Myoglobin Variants Reconstituted with Artificial Cofactors
Chao Guo, Robert J. Chadwick, Adam Foulis, Giada Bedendi, Andriy Lubskyy, Kyle J. Rodriguez, Michela M. Pellizzoni, Ross D. Milton, Rebecca Beveridge, Nico Bruns
ChemBioChem (2022)

Author Correction: Design and evolution of chimeric streptavidin for protein-enabled dual gold catalysis
Fadri Christoffel, Nico V. Igareta, Michela M. Pellizzoni, Laura Tiessler-Sala, Boris Lozhkin, Daniel C. Spiess, Agustí Lledós, Jean-Didier Maréchal, Ryan L. Peterson, Thomas R. Ward
Nature Catalysis (2022)

Engineered myoglobin as a catalyst for atom transfer radical cyclisation
Andriy Lubskyy, Chao Guo, Robert J. Chadwick, Alke Petri-Fink, Nico Bruns, Michela M. Pellizzoni
Chemical Communications (2022)

Design and evolution of chimeric streptavidin for protein-enabled dual gold catalysis
Fadri Christoffel, Nico V. Igareta, Michela M. Pellizzoni, Laura Tiessler-Sala, Boris Lozhkin, Daniel C. Spiess, Agustí Lledós, Jean-Didier Maréchal, Ryan L. Peterson, Thomas R. Ward
Nature Catalysis (2021)

Systematic engineering of artificial metalloenzymes for new-to-nature reactions
Tobias Vornholt, Fadri Christoffel, Michela M. Pellizzoni, Sven Panke, Thomas R. Ward, Markus Jeschek
Science Advances (2021)

Systematic Engineering of Artificial Metalloenzymes for New-to-Nature Reactions
Tobias Vornholt, Fadri Christoffel, Michela M. Pellizzoni, Sven Panke, Thomas R. Ward, Markus Jeschek
other (2020)

Rapid quantification of the malaria biomarker hemozoin by improved biocatalytically initiated precipitation atom transfer radical polymerizations
Samuel Raccio, Jonas Pollard, Ashley Djuhadi, Sandor Balog, Michela M. Pellizzoni, Kyle J. Rodriguez, Omar Rifaie-Graham, Nico Bruns
The Analyst (2020)

Biocatalytic ATRP in solution and on surfaces
Kyle J. Rodriguez, Michela M. Pellizzoni, Mohammad Divandari, Edmondo M. Benetti, Nico Bruns
Methods in Enzymology (2019)

Enzyme-initiated free radical polymerizations of vinyl monomers using horseradish peroxidase
Kyle J. Rodriguez, Michela M. Pellizzoni, Robert J. Chadwick, Chao Guo, Nico Bruns
Methods in Enzymology (2019)

Genetic Engineering of an Artificial Metalloenzyme for Transfer Hydrogenation of a Self-Immolative Substrate in Escherichia coli’s Periplasm
Jingming Zhao, Johannes G. Rebelein, Hendrik Mallin, Christian Trindler, Michela M. Pellizzoni, Thomas R. Ward
Journal of the American Chemical Society (2018)

Repurposing Biocatalysts to Control Radical Polymerizations
Kyle J. Rodriguez, Bernadetta Gajewska, Jonas Pollard, Michela M. Pellizzoni, Csaba Fodor, Nico Bruns
ACS Macro Letters (2018)

Chimeric Streptavidins as Host Proteins for Artificial Metalloenzymes
Michela M. Pellizzoni, Fabian Schwizer, Christopher W. Wood, Valerio Sabatino, Yoann Cotelle, Stefan Matile, Derek N. Woolfson, Thomas R. Ward
ACS Catal., 2018, 8 (2), pp 1476–1484 (2018)

Hybrid catalysts for C-H activation and other X-H insertion reactions

Artificial metalloenzymes and metalloDNAzymes in catalysis. From design to application. (2018)

Artificial Metalloenzymes: Reaction Scope and Optimization Strategies
Fabian Schwizer, Yasunori Okamoto, Tillmann Heinisch, Yifan Gu, Michela M. Pellizzoni, Vincent Lebrun, Raphael Reuter, Valentin Köhler, Jared C. Lewis, Thomas R. Ward
Chem. Rev. (2017)

Evaluation of Chemical Diversity of Biotinylated Chiral 1,3-Diamines as a Catalytic Moiety in Artificial Imine Reductase
Michela Pellizzoni, Giorgio Facchetti, Raffaella Gandolfi, Marco Fusè, Alessandro Contini, Isabella Rimoldi
ChemCatChem (2016)

Improving the catalytic performance of an artificial metalloenzyme by computational design
Tillmann Heinisch, Michela Pellizzoni, Marc Dürrenberger, Christine E. Tinberg, Valentin Köhler, Juliane Klehr, Daniel Häussinger, David Baker, Thomas R. Ward
Journal of the American Chemical Society (2015)

Simple 1,3-diamines and their application as ligands in ruthenium(II) catalysts for asymmetric transfer hydrogenation of aryl ketones
Giorgio Facchetti, Raffaella Gandolfi, Marco Fusè, Daniele Zerla, Edoardo Cesarotti, Michela Pellizzoni, Isabella Rimoldi
New Journal of Chemistry (2015)

Diastereoselectivity and catalytic activity in ruthenium complexes chiral at the metal centre
Daniele S. Zerla, Isabella Rimoldi, Edoardo Cesarotti, Giorgio Facchetti, Michela Pellizzoni, Marco Fusè
Journal of Organometallic Chemistry (2014)

8-Amino-5,6,7,8-tetrahydroquinolines as ligands in iridium(III) catalysts for the reduction of aryl ketones by asymmetric transfer hydrogenation (ATH)
Daniele Zerla, Giorgio Facchetti, Marco Fusè, Michela Pellizzoni, Carlo Castellano, Edoardo Cesarotti, Raffaella Gandolfi, Isabella Rimoldi
Tetrahedron Asymmetry (2014)

Cytotoxic effect of (1-methyl-1H-imidazol-2-yl)-methanamine and its derivatives in Pt^II complexes on human carcinoma cell lines: A comparative study with cisplatin
Nicola Ferri, Stefano Cazzaniga, Luca Mazzarella, Giuseppe Curigliano, Giorgio Lucchini, Daniele Zerla, Raffaella Gandolfi, Giorgio Facchetti, Michela Pellizzoni, Isabella Rimoldi
Bioorganic and Medicinal Chemistry (2013)

Enantioselective transfer hydrogenation of Aryl Ketones: Synthesis and 2D-NMR characterization of new 8-amino-5,6,7,8-tetrahydroquinoline Ru(II)-complexes
Isabella Rimoldi, Giorgio Facchetti, Edoardo Cesarotti, Michela Pellizzoni, Marco Fuse, Daniele Zerla
Current Organic Chemistry (2012)

"In situ" activation of racemic Ru ^II complexes: Separation of trans and cis species and their application in asymmetric reduction
Giorgio Facchetti, Edoardo Cesarotti, Michela Pellizzoni, Daniele Zerla, Isabella Rimoldi
European Journal of Inorganic Chemistry (2012)

Chemo- and biocatalytic strategies to obtain phenylisoserine, a lateral chain of Taxol by asymmetric reduction
Isabella Rimoldi, Michela Pellizzoni, Giorgio Facchetti, Francesco Molinari, Daniele Zerla, Raffaella Gandolfi
Tetrahedron Asymmetry (2011)

PELLIZZONI Michela

Enzyme-catalyzed ATRP