Person | Adolphe Merkle Institute | Université de Fribourg

FONG Khay

Alumni

Postdoctoral researcher, BioNanomaterials

Adolphe Merkle Institute Chemin des Verdiers 4 CH-1700 Fribourg Switzerland

Office:	C254
Phone:	+41 26 300 9527
Email:	khay.fong@unifr.ch
	0000-0002-0437-9332

Publications

Investigating the Behaviour of Lipid Nanoparticles Upon Meeting Biological Barriers in Colorectal Drug Delivery
Shiva Montasseri, Frithjof Herb, Thomas Bourke, Clovia Holdsworth, Robert Chapman, Livia Salvati Manni, Wye-Khay Fong
Colloids and Surfaces B: Biointerfaces , 114938 (2025)

Intermolecular Dynamics of Monoglyceride Mesophases with Their Biomacromolecular Corona
Wye-Khay Fong, Dimitri Vanhecke, Daniel Hauser, Sandor Balog, Philipp Lemal, Shiva Montasseri, Barbara Rothen-Rutishauser, Alke Petri-Fink
Molecular Pharmaceutics (2025)

Time-Resolved In Situ Small-Angle X-ray Scattering to Determine the Kinetics of Formation of Liquid Crystalline Structure in the Core of Polymeric Nanoparticles during and after Turbulent Mixing
Sophia R. Dasaro, Lucas D. Johnson, Malinda Salim, Vincent He, David Amelemah, Ellie Ponsonby-Thomas, Bryce Barber, Wye-Khay Fong, Jonathan Caukwell, Elizabeth Peach, Ben Li, Livia Salvati Manni, Nigel Kirby, Gregory G. Warr, Robert K. Prud’homme, Ben J. Boyd, Kurt Ristroph
Nano Letters (2025)

Lipidic drug delivery systems are responsive to the human microbiome
Jonathan Caukwell, Salvatore Assenza, Karl A. Hassan, Brett A. Neilan, Andrew J. Clulow, Livia Salvati Manni, Wye-Khay Fong
Journal of Colloid and Interface Science 677 , 293-302 (2025)

Machine Learning Microplastic Characterisation Surpasses Human Performance and Uncovers Labelling Errors in Public FTIR Data
Wye-Khay Fong, Frithjof Herb, Mario Boley
not found (2024)

H-bond network, interfacial tension and chain melting temperature govern phospholipid self-assembly in ionic liquids
Livia Salvati Manni, Wye-Khay Fong, Kathleen Wood, Nigel Kirby, Susanne Seibt, Rob Atkin, Gregory G. Warr
Journal of Colloid and Interface Science 657 , 320-326 (2024)

How small is the big problem? Small microplastics <300 μm abundant in marine surface waters of the Great Barrier Reef Marine Park
Maddison Carbery, Frithjof Herb, Julien Reynes, Christopher K. Pham, Wye-Khay Fong, Roman Lehner
Marine Pollution Bulletin 184 , 114179 (2022)

Hydrogen Sulfide-Responsive Bicontinuous Nanospheres
Daniel A. Paterson, Wye-Khay Fong, Sarah Hook, Allan B. Gamble
Biomacromolecules 22 , 4770-4782 (2021)

Synthesis of 2D Porous Crystalline Materials in Simulated Microgravity
Noemí Contreras‐Pereda, David Rodríguez‐San‐Miguel, Carlos Franco, Semih Sevim, João Pedro Vale, Eduardo Solano, Wye‐Khay Fong, Alessandra Del Giudice, Luciano Galantini, Raphael Pfattner, Salvador Pané, Tiago Sotto Mayor, Daniel Ruiz‐Molina, Josep Puigmartí‐Luis
Advanced Materials (2021)

Enzymatic hydrolysis of monoacylglycerols and their cyclopropanated derivatives: Molecular structure and nanostructure determine the rate of digestion
Livia Salvati Manni, Michael Duss, Salvatore Assenza, Ben J. Boyd, Ehud M. Landau, Wye-Khay Fong
Journal of Colloid and Interface Science (2021)

Understanding the assembly of amphiphilic additives in bulk and dispersed non-lamellar lipid-based matrices: Phosphorylation, H-bonding and ionisation
Marco F. Etter, Daria Dellenbach, Alke Petri-Fink, Barbara Rothen-Rutishauser, Ehud M. Landau, Wye-Khay Fong
Journal of Colloid and Interface Science (2020)

Lipid-based mesophases as matrices for nanoscale reactions
Livia Salvati Manni, Wye-Khay Fong, Raffaele Mezzenga
Nanoscale Horizons (2020)

Structural Transformation in Vesicles upon Hydrolysis of Phosphatidylethanolamine and Phosphatidylcholine with Phospholipase C
Wye-Khay Fong, Antoni Sánchez-Ferrer, Michael Rappolt, Ben J. Boyd, Raffaele Mezzenga
Langmuir (2019)

Nanoparticle Behaviour in Complex Media: Methods for Characterizing Physicochemical Properties, Evaluating Protein Corona Formation, and Implications for Biological Studies
Wye-Khay Fong, Thomas L. Moore, Sandor Balog, Dimitri Vanhecke, Laura Rodriguez-Lorenzo, Barbara Rothen-Rutishauser, Marco Lattuada, Alke Petri-Fink
Biological Responses to Nanoscale Particles , 101-150 (2019)

Photoswitchable Molecules in Long-Wavelength Light-Responsive Drug Delivery: From Molecular Design to Applications
Shiyang Jia, Wye-Khay Fong, Bim Graham, Ben J. Boyd
Chemistry of Materials (2018)

Hexosomes with undecylenic acid efficient against candida albicans
Marijana Mionić Ebersold, Milica Petrović, Wye-Khay Fong, Debora Bonvin, Heinrich Hofmann, Irena Milošević
Nanomaterials (2018)

Ice-Templated and Cross-Linked Amyloid Fibril Aerogel Scaffolds for Cell Growth
Gustav Nyström, Wye-Khay Fong, Raffaele Mezzenga
Biomacromolecules (2017)

Investigation of Donor–Acceptor Stenhouse Adducts as New Visible Wavelength-Responsive Switching Elements for Lipid-Based Liquid Crystalline Systems
Shiyang Jia, Joanne D. Du, Adrian Hawley, Wye-Khay Fong, Bim Graham, Ben J. Boyd
Langmuir (2017)

Dynamic formation of nanostructured particles from vesicles via invertase hydrolysis for on-demand delivery
Wye-Khay Fong, Antoni Sánchez-Ferrer, Francesco Giovanni Ortelli, Wenjie Sun, Ben J. Boyd, Raffaele Mezzenga
RSC Advances (2017)

Lipid-based drug delivery systems in the treatment of wet age-related macular degeneration
Joanne D. Du, Wye-Khay Fong, Suzanne Caliph, Ben J. Boyd
Drug Delivery and Translational Research (2016)

Lyotropic Liquid Crystalline Cubic Phases as Versatile Host Matrices for Membrane-Bound Enzymes
Wenjie Sun, Jijo J. Vallooran, Wye-Khay Fong, Raffaele Mezzenga
Journal of Physical Chemistry Letters (2016)

External manipulation of nanostructure in photoresponsive lipid depot matrix to control and predict drug release in vivo
Wye-Khay Fong, Tracey L. Hanley, Benjamin Thierry, Adrian Hawley, Ben J. Boyd, Cornelia B. Landersdorfer
Journal of Controlled Release (2016)

Responsive self-assembled nanostructured lipid systems for drug delivery and diagnostics
Wye-Khay Fong, Renata Negrini, Jijo J. Vallooran, Raffaele Mezzenga, Ben J. Boyd
Journal of Colloid and Interface Science (2016)

Oil transfer converts phosphatidylcholine vesicles into nonlamellar lyotropic liquid crystalline particles
Isabelle Martiel, Stephan Handschin, Wye-Khay Fong, Laurent Sagalowicz, Raffaele Mezzenga
Langmuir (2015)

PH-responsive lyotropic liquid crystals and their potential therapeutic role in cancer treatment
Renata Negrini, Wye-Khay Fong, Ben J. Boyd, Raffaele Mezzenga
Chemical Communications (2015)

Phospholipid-based self-assembled mesophase systems for light-activated drug delivery
Joanne D. Du, Wye-Khay Fong, Stefan Salentinig, Suzanne M. Caliph, Adrian Hawley, Ben J. Boyd
Physical Chemistry Chemical Physics (2015)

Generation of geometrically ordered lipid-based liquid-crystalline nanoparticles using biologically relevant enzymatic processing
Wye Khay Fong, Stefan Salentinig, Clive A. Prestidge, Raffaele Mezzenga, Adrian Hawley, Ben J. Boyd
Langmuir (2014)

Understanding the photothermal heating effect in non-lamellar liquid crystalline systems, and the design of new mixed lipid systems for photothermal on-demand drug delivery
Wye-Khay Fong, Tracey L. Hanley, Benjamin Thierry, Adam Tilley, Nigel Kirby, Lynne J. Waddington, Ben J. Boyd
Physical Chemistry Chemical Physics (2014)

Novel spiropyran amphiphiles and their application as light-responsive liquid crystalline components
Kristian J. Tangso, Wye-Khay Fong, Tamim Darwish, Nigel Kirby, Ben J. Boyd, Tracey L. Hanley
Journal of Physical Chemistry B (2013)

Alkylation of spiropyran moiety provides reversible photo-control over nanostructured soft materials
Wye-Khay Fong, Nino Malic, Richard A. Evans, Adrian Hawley, Ben J. Boyd, Tracey L. Hanley
Biointerphases (2012)

Controlling the nanostructure of gold nanorod-lyotropic liquid-crystalline hybrid materials using near-infrared laser irradiation
Wye-Khay Fong, Tracey L. Hanley, Benjamin Thierry, Nigel Kirby, Lynne J. Waddington, Ben J. Boyd
Langmuir (2012)

Stimuli-responsive lipid-based self-assembled systems
Ben J. Boyd, Wye‐Khay Fong
Self-Assembled Supramolecular Architectures: Lyotropic Liquid Crystals (2012)

Evaluating the link between self-assembled mesophase structure and drug release
Stephanie Phan, Wye-Khay Fong, Nigel Kirby, Tracey Hanley, Ben J. Boyd
International Journal of Pharmaceutics (2011)

Plasmonic nanorods provide reversible control over nanostructure of self-assembled drug delivery materials
Wye-Khay Fong, Tracey L. Hanley, Benjamin Thierry, Nigel Kirby, Ben J. Boyd
Langmuir (2010)

Responsive lipid-based mesophase materials - opportunity for a new class of on demand drug delivery system

conference-paper (2009)

Stimuli responsive liquid crystals provide 'on-demand' drug delivery in vitro and in vivo
Wye-Khay Fong, Tracey Hanley, Ben J. Boyd
Journal of Controlled Release (2009)