Person | Adolphe Merkle Institute | Université de Fribourg

ALMEIDA Mauro

BioNanomaterials

Adolphe Merkle Institute Chemin des Verdiers 4 CH-1700 Fribourg Switzerland

Office:	C246
Phone:	+41 26 300 9522
Email:	mauro.sousadealmeida@unifr.ch
	0000-0001-7314-0192

Projects lead

In Vitro Lung Co-Culture Model for Evaluating Therapeutic Treatments and Inflammatory Responses

In Vitro Lung Co-Culture Model for Evaluating Anti-Inflammatory Effects of Herbal Medicines

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Projects team

Particle Stability and Stimuli-Responsiveness

Surface and intrinsic properties of nanomaterials can be exploited to trigger receptor-mediated uptake…

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Trafficking of Nanomaterials

Uptake, intracellular trafficking, and exocytosis are processes that affect cytotoxicity, cell behavior,…

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Stimulation of cellular endocytosis for sensing and enhancing nanoparticle uptake

With the development of nanotechnology, nanoparticles ...

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Swiss NanoAnalytics

Platform for analytical services and consulting

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Theses

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Deciphering nanoparticle endocytosis to improve therapeutic strategies, 2023
Publications

Does the surface charge of the nanoparticles drive nanoparticle–cell membrane interactions?
Sandor Balog, Mauro Sousa de Almeida, Patricia Taladriz-Blanco, Barbara Rothen-Rutishauser, Alke Petri-Fink
Current Opinion in Biotechnology 87 , 103128 (2024)

The Effect of Substrate Properties on Cellular Behavior and Nanoparticle Uptake in Human Fibroblasts and Epithelial Cells
Mauro Sousa de Almeida, Aaron Lee, Fabian Itel, Katharina Maniura-Weber, Alke Petri-Fink, Barbara Rothen-Rutishauser
Nanomaterials 14 , 342 (2024)

Immunostimulatory nanoparticles delivering cytokines as a novel cancer nanoadjuvant to empower glioblastoma immunotherapy
Flávia Sousa, Henry Lee, Mauro Almeida, Amelie Bazzoni, Barbara Rothen-Rutishauser, Alke Petri-Fink
Drug Delivery and Translational Research (2023)

Cellular Uptake of Silica Particles Influences EGFR Signaling Pathway and is Affected in Response to EGF

International journal of nanomedicine (2023)

Multi-Functionalized Heteroduplex Antisense Oligonucleotides for Targeted Intracellular Delivery and Gene Silencing in HeLa Cells
Mauro Sousa de Almeida, Barbara Rothen-Rutishauser, Michael Mayer, Maria Taskova
Biomedicines 10 , 2096 (2022)

Intracellular gold nanoparticles influence light scattering and facilitate amplified spontaneous emission generation.
Phattadon Yajan, Nursidik Yulianto, Matthias Saba, Agus Budi Dharmawan, Mauro Sousa de Almeida, Patricia Taladriz-Blanco, Hutomo Suryo Wasisto, Barbara Rothen-Rutishauser, Alke Petri-Fink, Dedy Septiadi
Journal of Colloid and Interface Science 622 , 914-923 (2022)

Cellular Uptake of Silica and Gold Nanoparticles Induces Early Activation of Nuclear Receptor NR4A1
Mauro Sousa de Almeida, Patricia Taladriz-Blanco, Barbara Drasler, Sandor Balog, Phattadon Yajan, Alke Petri-Fink, Barbara Rothen-Rutishauser
Nanomaterials 12 , 690 (2022)

Substrate stiffness reduces particle uptake by epithelial cells and macrophages in a size-dependent manner through mechanoregulation
Aaron Lee, Mauro Sousa de Almeida, Daela Milinkovic, Dedy Septiadi, Patricia Taladriz-Blanco, Céline Loussert-Fonta, Sandor Balog, Amelie Bazzoni, Barbara Rothen-Rutishauser, Alke Petri-Fink
Nanoscale 14 , 15141-15155 (2022)

Particle Stiffness and Surface Topography Determine Macrophage‐Mediated Removal of Surface Adsorbed Particles
Aaron Lee, Dedy Septiadi, Patricia Taladriz‐Blanco, Mauro Almeida, Laetitia Haeni, Miguel Spuch‐Calvar, Wildan Abdussalam, Barbara Rothen‐Rutishauser, Alke Petri‐Fink
Advanced Healthcare Materials 10 , 2001667 (2021)

Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine
Mauro Sousa de Almeida, Eva Susnik, Barbara Drasler, Patricia Taladriz-Blanco, Alke Petri-Fink, Barbara Rothen-Rutishauser
Chemical Society Reviews 50 , 5397-5434 (2021)

An inflamed human alveolar model for testing the efficiency of anti-inflammatory drugs in vitro

data-set (2020)

miR-145-loaded micelleplexes as a novel therapeutic strategy to inhibit proliferation and migration of osteosarcoma cells
Mariana Magalhães, Mauro Almeida, Elisiário Tavares-da-Silva, Fernanda M.F. Roleira, Carla Varela, Joana Jorge, Ana Cristina Gonçalves, Rui Albuquerque Carvalho, Francisco Veiga, Ana Cláudia Santos, Ana Figueiras
European Journal of Pharmaceutical Sciences 123 , 28-42 (2018)

Poloxamers, poloxamines and polymeric micelles: Definition, structure and therapeutic applications in cancer
Mauro Almeida, Mariana Magalhães, Francisco Veiga, Ana Figueiras
Journal of Polymer Research 25 (2017)

ALMEIDA Mauro

In Vitro Lung Co-Culture Model for Evaluating Therapeutic Treatments and Inflammatory Responses

Particle Stability and Stimuli-Responsiveness

Trafficking of Nanomaterials

Stimulation of cellular endocytosis for sensing and enhancing nanoparticle uptake

Swiss NanoAnalytics