Publications

Polymersome-based protein drug delivery – quo vadis?
Micael G. Gouveia, Justus P. Wesseler, Jobbe Ramaekers, Christoph Weder, Philip B. V. Scholten, Nico Bruns
Chemical Society Reviews (2023)

 

Peptide‐Reinforced Amphiphilic Polymer Conetworks
Sara T. R. Velasquez, Daseul Jang, Peter Jenkins, Peng Liu, Liu Yang, LaShanda T. J. Korley, Nico Bruns
Advanced Functional Materials , 2207317 (2022)

 

Engineered myoglobin as a catalyst for atom transfer radical cyclisation
Andriy Lubskyy, Chao Guo, Robert J. Chadwick, Alke Petri-Fink, Nico Bruns, Michela M. Pellizzoni
Chemical Communications 58 , 10989-10992 (2022)

 

Peroxidase Activity of Myoglobin Variants Reconstituted with Artificial Cofactors
Chao Guo, Robert J. Chadwick, Adam Foulis, Giada Bedendi, Andriy Lubskyy, Kyle J. Rodriguez, Michela M. Pellizzoni, Ross D. Milton, Rebecca Beveridge, Nico Bruns
ChemBioChem (2022)

 

Polymersomes-mediated delivery of CSF1R inhibitor to tumor associated macrophages promotes M2 to M1-like macrophage repolarization
Manuel Rodriguez‐Perdigon, Sètuhn Jimaja, Laetitia Haeni, Nico Bruns, Barbara Rothen‐Rutishauser, Curzio Rüegg
Macromolecular Bioscience , 2200168 (2022)

 

Donor‐acceptor Stenhouse adduct-polydimethylsiloxane-conjugates for enhanced photoswitching in bulk polymers
Michèle Clerc, Cem Tekin, Sebastian Ulrich, Rafael V. M. Freire, Stefan Salentinig, Nico Bruns, Luciano F. Boesel
Macromolecular Rapid Communications , 2200120 (2022)

 

Bioengineered Protein Nanocage by Small Heat Shock Proteins Delivering mTERT siRNA for Enhanced Colorectal Cancer Suppression
Hao Wang, Ning Liu, Fuxu Yang, Nannan Hu, Mingyue Wang, Meiying Cui, Nico Bruns, Xingang Guan
ACS Applied Bio Materials 5 , 1330-1340 (2022)

 

Nano-3D-printed photochromic micro-objects

Small (2021)

 

Infiltration of Proteins in Cholesteric Cellulose Structures
Livia K. Bast, Konrad W. Klockars, Luiz G. Greca, Orlando J. Rojas, Blaise L. Tardy, Nico Bruns
Biomacromolecules 22 , 2067-2080 (2021)

 

A methodology for remote microwave sterilization applicable to the coronavirus and other pathogens using retrodirective antenna arrays

IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology (2021)

 

Promoting the Furan Ring‐Opening Reaction to Access New Donor–Acceptor Stenhouse Adducts with Hexafluoroisopropanol
Michèle Clerc, Friedrich Stricker, Sebastian Ulrich, Miranda Sroda, Nico Bruns, Luciano F. Boesel, Javier Read de Alaniz
Angewandte Chemie 133 , 10307-10315 (2021)

 

Promoting the furan ring opening reaction to access new donor–acceptor stenhouse adducts with hexafluoroisopropanol

Angewandte Chemie International Edition (2021)

 

Shear stress-responsive polymersome nanoreactors inspired by the marine bioluminescence of dinoflagellates
Omar Rifaie‐Graham, Nikolas F. B. Galensowske, Charlie Dean, Jonas Pollard, Sandor Balog, Micael G. Gouveia, Mohamed Chami, Antoine Vian, Esther Amstad, Marco Lattuada, Nico Bruns
Angewandte Chemie International Edition 60 , 904-909 (2021)

 

Stabilizing Enzymes within Polymersomes by Coencapsulation of Trehalose
Maria Valentina Dinu, Ionel Adrian Dinu, Sina S. Saxer, Wolfgang Meier, Uwe Pieles, Nico Bruns
Biomacromolecules 22 , 134-145 (2021)

 

Rapid quantification of the malaria biomarker hemozoin by improved biocatalytically initiated precipitation atom transfer radical polymerizations
Samuel Raccio, Jonas Pollard, Ashley Djuhadi, Sandor Balog, Michela M. Pellizzoni, Kyle J. Rodriguez, Omar Rifaie-Graham, Nico Bruns
The Analyst 145 , 7741-7751 (2020)

 

Silk Sericin-Polylactide Protein–Polymer Conjugates as Biodegradable Amphiphilic Materials and Their Application in Drug Release Systems
Kanittha Boonpavanitchakul, Livia K. Bast, Nico Bruns, Rathanawan Magaraphan
Bioconjugate Chemistry 31 , 2312-2324 (2020)

 

Functional membranes based on amphiphilic polymer co-networks
Sebastian Ulrich, Luciano F. Boesel, Nico Bruns
Polymer Chemistry Series , 331-363 (2020)

 

Tuning the Properties of a UV-Polymerized, Cross-Linked Solid Polymer Electrolyte for Lithium Batteries
Preston Sutton, Martino Airoldi, Luca Porcarelli, Jorge L. Olmedo-Martínez, Clément Mugemana, Nico Bruns, David Mecerreyes, Ullrich Steiner, Ilja Gunkel
Polymers 12 , 595 (2020)

 

Self-healing metallo-supramolecular amphiphilic polymer conetworks
Clément Mugemana, Patrick Grysan, Reiner Dieden, David Ruch, Nico Bruns, Philippe Dubois
Macromolecular Chemistry and Physics 221 , 1900432 (2020)

 

Biocatalytically Initiated Precipitation Atom Transfer Radical Polymerization (ATRP) as a Quantitative Method for Hemoglobin Detection in Biological Fluids
Jonas Pollard, Omar Rifaie-Graham, Samuel Raccio, Annabelle Davey, Sandor Balog, Nico Bruns
Analytical Chemistry 92 , 1162-1170 (2020)

 

Virtual special issue "Biomimetic Polymers"
Nico Bruns, Thomas Scheibel
European Polymer Journal 122 , 109370 (2020)

 

Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis
Omar Rifaie-Graham, Jonas Pollard, Samuel Raccio, Sandor Balog, Sebastian Rusch, María Andrea Hernández-Castañeda, Pierre-Yves Mantel, Hans-Peter Beck, Nico Bruns
Nature Communications 10 (2019)

 

Pyranine-modified amphiphilic polymer conetworks as fluorescent ratiometric pH sensors
Sebastian Ulrich, Alina Osypova, Guido Panzarasa, René M. Rossi, Nico Bruns, Luciano F. Boesel
Macromolecular Rapid Communications 40 , 1900360 (2019)

 

Light-responsive block copolymers with a spiropyran located at the block junction
Edward A. Apebende, Laurent Dubois, Nico Bruns
European Polymer Journal 119 , 83-93 (2019)

 

Biocatalytic ATRP in solution and on surfaces
Kyle J. Rodriguez, Michela M. Pellizzoni, Mohammad Divandari, Edmondo M. Benetti, Nico Bruns
Methods in Enzymology , 263-290 (2019)

 

Preface
Nico Bruns, Katja Loos
Methods in Enzymology , xv-xix (2019)

 

Enzymatic Polymerizations, Volume 627

Methods in Enzymology (2019)

 

Enzyme-initiated free radical polymerizations of vinyl monomers using horseradish peroxidase
Kyle J. Rodriguez, Michela M. Pellizzoni, Robert J. Chadwick, Chao Guo, Nico Bruns
Methods in Enzymology , 249-262 (2019)

 

Bio-inspired polymersome nanoreactors
Omar Rifaie-Graham, Edward A. Apebende, Nico Bruns
CHIMIA 73 , 21 (2019)

 

Chlorophyll derivatives as catalysts and comonomers for atom transfer radical polymerizations
Bernadetta Gajewska, Samuel Raccio, Kyle J. Rodriguez, Nico Bruns
Polymer Chemistry 10 , 125-135 (2019)

 

Effects of Silk Degumming Process on Physicochemical, Tensile, and Optical Properties of Regenerated Silk Fibroin
Kira Nultsch, Livia K. Bast, Muriel Näf, Salima El Yakhlifi, Nico Bruns, Oliver Germershaus
Macromolecular Materials and Engineering 303 , 1800408 (2018)

 

The kinetics of hematin crystallization measured by depolarized light scattering
Omar Rifaie-Graham, Xiao Hua, Nico Bruns, Sandor Balog
Small 14 , 1802295 (2018)

 

Repurposing Biocatalysts to Control Radical Polymerizations
Kyle J. Rodriguez, Bernadetta Gajewska, Jonas Pollard, Michela M. Pellizzoni, Csaba Fodor, Nico Bruns
ACS Macro Letters 7 , 1111-1119 (2018)

 

DNA-Coated Functional Oil Droplets
Alessio Caciagli, Mykolas Zupkauskas, Aviad Levin, Tuomas P. J. Knowles, Clément Mugemana, Nico Bruns, Thomas O’Neill, William J. Frith, Erika Eiser
Langmuir 34 , 10073-10080 (2018)

 

Biocatalytic ATRP
Jonas Pollard, Nico Bruns
ACS Symposium Series , 379-393 (2018)

 

Wide Range of Functionalized Poly(N-alkyl acrylamide)-Based Amphiphilic Polymer Conetworks via Active Ester Precursors
Sebastian Ulrich, Amin Sadeghpour, René M. Rossi, Nico Bruns, Luciano F. Boesel
Macromolecules 51 , 5267-5277 (2018)

 

Wavelength-Selective Light-Responsive DASA-Functionalized Polymersome Nanoreactors
Omar Rifaie-Graham, Sebastian Ulrich, Nikolas F. B. Galensowske, Sandor Balog, Mohamed Chami, Daniel Rentsch, James R. Hemmer, Javier Read de Alaniz, Luciano F. Boesel, Nico Bruns
Journal of the American Chemical Society 140 , 8027-8036 (2018)

 

Self-Reporting Fiber-Reinforced Composites That Mimic the Ability of Biological Materials to Sense and Report Damage
Omar Rifaie-Graham, Edward A. Apebende, Livia K. Bast, Nico Bruns
Advanced Materials 30 , 1705483 (2018)

 

Bioinspiration Across All Length Scales of Materials
Silvia Vignolini, Nico Bruns
Advanced Materials 30 , 1801687 (2018)

 

Bioinspired Materials: (Adv. Mater. 19/2018)

Advanced Materials 30 , 1870130 (2018)

 

Controlling Enzymatic Polymerization from Surfaces with Switchable Bioaffinity
Mohammad Divandari, Jonas Pollard, Ella Dehghani, Nico Bruns, Edmondo M. Benetti
Biomacromolecules 18 , 4261-4270 (2017)

 

Structural Behavior of Cylindrical Polystyrene-block-Poly(ethylene-butylene)-block-Polystyrene (SEBS) Triblock Copolymer Containing MWCNTs: On the Influence of Nanoparticle Surface Modification
Noushin Hasanabadi, Hossein Nazockdast, Bernadetta Gajewska, Sandor Balog, Ilja Gunkel, Nico Bruns, Marco Lattuada
Macromolecular Chemistry and Physics 218 , 1700231 (2017)

 

Visible Light-Responsive DASA-Polymer Conjugates
Sebastian Ulrich, James R. Hemmer, Zachariah A. Page, Neil D. Dolinski, Omar Rifaie-Graham, Nico Bruns, Craig J. Hawker, Luciano F. Boesel, Javier Read de Alaniz
ACS Macro Letters 6 , 738-742 (2017)

 

Biocatalytic atom transfer radical polymerization in a protein cage nanoreactor
Kasper Renggli, Nora Sauter, Martin Rother, Martin G. Nussbaumer, Raphael Urbani, Thomas Pfohl, Nico Bruns
Polymer Chemistry 8 , 2133-2136 (2017)

 

Chapter 11. Self-reporting Polymeric Materials with Mechanochromic Properties
Jose V. Araujo, Omar Rifaie-Graham, Edward A. Apebende, Nico Bruns
Polymer Chemistry Series , 354-401 (2017)

 

Protein cages and synthetic polymers: a fruitful symbiosis for drug delivery applications, bionanotechnology and materials science
Martin Rother, Martin G. Nussbaumer, Kasper Renggli, Nico Bruns
Chemical Society Reviews 45 , 6213-6249 (2016)

 

Laccase-catalyzed controlled radical polymerization of N-vinylimidazole
Csaba Fodor, Bernadetta Gajewska, Omar Rifaie-Graham, Edward A. Apebende, Jonas Pollard, Nico Bruns
Polymer Chemistry 7 , 6617-6625 (2016)

 

Preface

Polymer Chemistry Series , P007-P009 (2016)

 

Bio-inspired Polymers

Polymer Chemistry Series (2016)

 

Using the dendritic polymer PAMAM to form gold nanoparticles in the protein cage thermosome
Martin G. Nussbaumer, Christoph Bisig, Nico Bruns
Chemical Communications 52 , 10537-10539 (2016)

 

Chaperonin-Dendrimer Conjugates for siRNA Delivery
Martin G. Nussbaumer, Jason T. Duskey, Martin Rother, Kasper Renggli, Mohamed Chami, Nico Bruns
Advanced Science 3 , 1600046 (2016)

 

Self-Sealing and Puncture Resistant Breathable Membranes for Water-Evaporation Applications
Martin Rother, Jonas Barmettler, Andreas Reichmuth, Jose V. Araujo, Christian Rytka, Olfa Glaied, Uwe Pieles, Nico Bruns
Advanced Materials 27 , 6620-6624 (2015)

 

Filling Polymersomes with Polymers by Peroxidase-Catalyzed Atom Transfer Radical Polymerization
Maria Valentina Dinu, Mariana Spulber, Kasper Renggli, Dalin Wu, Christophe A. Monnier, Alke Petri-Fink, Nico Bruns
Macromolecular Rapid Communications 36 , 507-514 (2015)

 

Reduction-Sensitive Amphiphilic Triblock Copolymers Self-Assemble Into Stimuli-Responsive Micelles for Drug Delivery
Smahan Toughraï, Violeta Malinova, Raffaello Masciadri, Sindhu Menon, Pascal Tanner, Cornelia Palivan, Nico Bruns, Wolfgang Meier
Macromolecular Bioscience 15 , 481-489 (2015)

 

Polymeric Particulates for Subunit Vaccine Delivery
Thomas Schuster, Martin Nussbaumer, Patric Baumann, Nico Bruns, Wolfgang Meier, Anja Car
Advances in Delivery Science and Technology , 181-201 (2014)

 

pH-Responsive PDMS-b-PDMAEMA Micelles for Intracellular Anticancer Drug Delivery
Anja Car, Patric Baumann, Jason T. Duskey, Mohamed Chami, Nico Bruns, Wolfgang Meier
Biomacromolecules 15 , 3235-3245 (2014)

 

From Membrane to Skin: Aqueous Permeation Control Through Light-Responsive Amphiphilic Polymer Co-Networks
Katrin Schöller, Sabrina Küpfer, Lukas Baumann, Patrick M. Hoyer, Damien de Courten, René M. Rossi, Aliaksei Vetushka, Martin Wolf, Nico Bruns, Lukas J. Scherer
Advanced Functional Materials 24 , 5194-5201 (2014)

 

Mechanical unfolding of a fluorescent protein enables self-reporting of damage in carbon-fibre-reinforced composites
Samuel Lörcher, Thomas Winkler, Katarzyna Makyła, Claudiane Ouellet-Plamondon, Ingo Burgert, Nico Bruns
Journal of Materials Chemistry A 2 , 6231 (2014)

 

Poly(N-vinylpyrrolidone)-Poly(dimethylsiloxane)-Based Polymersome Nanoreactors for Laccase-Catalyzed Biotransformations
Mariana Spulber, Patric Baumann, Sina S. Saxer, Uwe Pieles, Wolfgang Meier, Nico Bruns
Biomacromolecules 15 , 1469-1475 (2014)

 

A Chaperonin as Protein Nanoreactor for Atom-Transfer Radical Polymerization
Kasper Renggli, Martin G. Nussbaumer, Raphael Urbani, Thomas Pfohl, Nico Bruns
Angewandte Chemie International Edition 53 , 1443-1447 (2014)

 

Combining Polymers with the Functionality of Proteins: New Concepts for Atom Transfer Radical Polymerization, Nanoreactors and Damage Self-reporting Materials
Nico Bruns, Samuel Lörcher, Katarzyna Makyła, Jonas Pollarda, Kasper Renggli, Mariana Spulber
CHIMIA 67 , 777 (2013)

 

Real-Time Viscosity and Mass Density Sensors Requiring Microliter Sample Volume Based on Nanomechanical Resonators
Benjamin A. Bircher, Luc Duempelmann, Kasper Renggli, Hans Peter Lang, Christoph Gerber, Nico Bruns, Thomas Braun
Analytical Chemistry 85 , 8676-8683 (2013)

 

Printing enzymes for colorimetric assays on paper
Roger Marti, David Spichiger
CHIMIA 67 , 648 (2013)

 

Hemoglobin and Red Blood Cells Catalyze Atom Transfer Radical Polymerization
Tilana B. Silva, Mariana Spulber, Marzena K. Kocik, Farzad Seidi, Himanshu Charan, Martin Rother, Severin J. Sigg, Kasper Renggli, Gergely Kali, Nico Bruns
Biomacromolecules 14 , 2703-2712 (2013)

 

Photoreaction of a Hydroxyalkyphenone with the Membrane of Polymersomes: A Versatile Method To Generate Semipermeable Nanoreactors
Mariana Spulber, Adrian Najer, Katharina Winkelbach, Olfa Glaied, Marcus Waser, Uwe Pieles, Wolfgang Meier, Nico Bruns
Journal of the American Chemical Society 135 , 9204-9212 (2013)

 

Fluorescent Protein Senses and Reports Mechanical Damage in Glass-Fiber-Reinforced Polymer Composites
Katarzyna Makyła, Christoph Müller, Samuel Lörcher, Thomas Winkler, Martin G. Nussbaumer, Michaela Eder, Nico Bruns
Advanced Materials 25 , 2701-2706 (2013)

 

Biocatalytic ATRP: Controlled Radical Polymerizations Mediated by Enzymes
Kasper Renggli, Mariana Spulber, Jonas Pollard, Martin Rother, Nico Bruns
Green Polymer Chemistry: Biocatalysis and Materials II , 163-171 (2013)

 

ATRPases: enzymes as catalysts for atom transfer radical polymerization
Severin J. Sigg, Farzad Seidi, Kasper Renggli, Tilana B. Silva, Gergely Kali, Nico Bruns
CHIMIA 66 , 66 (2012)

 

Use of a novel initiator for synthesis of amino-end functionalized polystyrene (NH2-PS) by atom transfer radical polymerization
Ali Pourjavadi, Farzad Seidi, Payam Eftekhar Jahromi, Hamid Salimi, Saeed Roshan, Ali Najafi, Nico Bruns
Journal of Polymer Research 19 (2012)

 

ATRPases: Using Nature's Catalysts in Atom Transfer Radical Polymerizations
Gergely Kali, Tilana B. Silva, Severin J. Sigg, Farzad Seidi, Kasper Renggli, Nico Bruns
ACS Symposium Series , 171-181 (2012)

 

Horseradish Peroxidase as a Catalyst for Atom Transfer Radical Polymerization
Severin J. Sigg, Farzad Seidi, Kasper Renggli, Tilana B. Silva, Gergely Kali, Nico Bruns
Macromolecular Rapid Communications 32 , 1710-1715 (2011)

 

Exploiting Dimerization of Purely Peptidic Amphiphiles to Form Vesicles
Thomas B. Schuster, Dirk de Bruyn Ouboter, Nico Bruns, Wolfgang Meier
Small 7 , 2158-2162 (2011)

 

Phase Behavior of Vesicle-Forming Block Copolymers in Aqueous Solutions
Jörg Braun, Nico Bruns, Thomas Pfohl, Wolfgang Meier
Macromolecular Chemistry and Physics 212 , 1245-1254 (2011)

 

Solid-Solid Interface Adsorption of Proteins and Enzymes in Nanophase-Separated Amphiphilic Conetworks
Stephan Dech, Tobias Cramer, Reinhild Ladisch, Nico Bruns, Joerg C. Tiller
Biomacromolecules 12 , 1594-1601 (2011)

 

Selective and Responsive Nanoreactors
Kasper Renggli, Patric Baumann, Karolina Langowska, Ozana Onaca, Nico Bruns, Wolfgang Meier
Advanced Functional Materials 21 , 1241-1259 (2011)

 

Self-Reporting Materials: Protein-Mediated Visual Indication of Damage in a Bulk Polymer
Nico Bruns, Douglas S. Clark
CHIMIA 65 , 245 (2011)

 

Biocompatible Functionalization of Polymersome Surfaces: A New Approach to Surface Immobilization and Cell Targeting Using Polymersomes
Stefan Egli, Martin G. Nussbaumer, Vimalkumar Balasubramanian, Mohamed Chami, Nico Bruns, Cornelia Palivan, Wolfgang Meier
Journal of the American Chemical Society 133 , 4476-4483 (2011)

 

Functionalization of Block Copolymer Vesicle Surfaces
Stefan Egli, Helmut Schlaad, Nico Bruns, Wolfgang Meier
Polymers 3 , 252-280 (2011)

 

Amphiphilic Polymer Conetworks as Matrices for Phase Transfer Reactions
Nico Bruns, Michael Hanko, Stephan Dech, Reinhild Ladisch, Jan Tobis, Joerg C. Tiller
Macromolecular Symposia 291-292 , 293-301 (2010)

 

Solid or Swollen Polymer-Protein Hybrid Materials
Kasper Renggli, Nico Bruns
ACS Symposium Series , 17-34 (2010)

 

Mechanical Nanosensor Based on FRET within a Thermosome: Damage-Reporting Polymeric Materials
Nico Bruns, Katarzyna Pustelny, Lisa M. Bergeron, Timothy A. Whitehead, Douglas S. Clark
Angewandte Chemie International Edition 48 , 5666-5669 (2009)

 

Amphiphilic conetworks as activating carriers for the enhancement of enzymatic activity in supercritical CO2
Nico Bruns, Willi Bannwarth, Joerg C. Tiller
Biotechnology and Bioengineering 101 , 19-26 (2008)

 

Optical biochemical sensor for determining hydroperoxides in nonpolar organic liquids as archetype for sensors consisting of amphiphilic conetworks as immobilisation matrices
Michael Hanko, Nico Bruns, Joerg C. Tiller, Jürgen Heinze
Analytical and Bioanalytical Chemistry 386 , 1273-1283 (2006)

 

Nanophase-separated Amphiphilic conetworks as versatile matrixes for optical chemical and biochemical sensors
Michael Hanko, Nico Bruns, Sara Rentmeister, Jörg C. Tiller, Jürgen Heinze
Analytical Chemistry 78 , 6376-6383 (2006)

 

Nanophasic amphiphilic conetworks with a fluorophilic phase
Nico Bruns, Joerg C. Tiller
Macromolecules 39 , 4386-4394 (2006)

 

Nanophase separated amphiphilic microbeads
Gabriela Savin, Nico Bruns, Yi Thomann, Joerg C. Tiller
Macromolecules 38 , 7536-7539 (2005)

 

Nanophase separated amphiphilic conetwork coatings and membranes
Nico Bruns, Jonas Scherble, Laura Hartmann, Ralf Thomann, Béla Iván, Rolf Mülhaupt, Joerg C. Tiller
Macromolecules 38 , 2431-2438 (2005)

 

Amphiphilic network as nanoreactor for enzymes in organic solvents
Nico Bruns, Joerg C. Tiller
Nano Letters 5 , 45-48 (2005)

 

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